TDO2 antibody (AA 137-406)

Catalog No. ABIN6148969

Product Details anti-TDO2 Antibody

Target: TDO2 (Tryptophan 2,3-Dioxygenase (TDO2))

Binding Specificity: AA 137-406

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TDO2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ALDFNDFREY LSPASGFQSL QFRLLENKIG VLQNMRVPYN RRHYRDNFKG EENELLLKSE QEKTLLELVE AWLERTPGLE PHGFNFWGKL EKNITRGLEE EFIRIQAKEE SEEKEEQVAE FQKQKEVLLS LFDEKRHEHL LSKGERRLSY RALQGALMIY FYREEPRFQV PFQLLTSLMD IDSLMTKWRY NHVCMVHRML GSKAGTGGSS GYHYLRSTVS DRYKVFVDLF NLSTYLIPRH WIPKMNPTIH KFLYTAEYCD SSYFSSDESD

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 137-406 of human TDO2 (NP_005642.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TDO2

Target: TDO2 (Tryptophan 2,3-Dioxygenase (TDO2))

Alternative Name: TDO2 (TDO2 Products)

Background: This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism.,TDO2,TDO,TO,TPH2,TRPO,tryptophan 2,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,TDO2

Molecular Weight: 47 kDa

Gene ID: 6999

UniProt: P48775