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TAP1 antibody (AA 524-808)
TAP1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TAP1 Antibody
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Target
See all TAP1 Antibodies
TAP1
(Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1))
Binding Specificity
All epitopes for TAP1 antibodies
AA 524-808
Reactivity
All reactivities for TAP1 antibodies
Human
Host
All hosts for TAP1 antibodies
Rabbit
Clonality
All clonalities for TAP1 antibodies
Polyclonal
Conjugate
All conjugates for TAP1 antibodies
This TAP1 antibody is un-conjugated
Application
All applications for TAP1 antibodies
Western Blotting (WB)
Sequence
IYPRVQKAVG SSEKIFEYLD RTPRCPPSGL LTPLHLEGLV QFQDVSFAYP NRPDVLVLQG LTFTLRPGEV TALVGPNGSG KSTVAALLQN LYQPTGGQLL LDGKPLPQYE HRYLHRQVAA VGQEPQVFGR SLQENIAYGL TQKPTMEEIT AAAVKSGAHS FISGLPQGYD TEVDEAGSQL SGGQRQAVAL ARALIRKPCV LILDDATSAL DANSQLQVEQ LLYESPERYS RSVLLITQHL SLVEQADHIL FLEGGAIREG GTHQQLMEKK GCYWAMVQAP ADAPE
Cross-Reactivity
Human, Mouse
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 524-808 of human TAP1 (NP_000584.2).
Isotype
IgG
Top Product
Discover our top product TAP1 Primary Antibody
Alternatives
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anti-Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1) (Middle Region) antibody
TAP1
Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for TAP1
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Target
TAP1
(Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1))
Alternative Name
TAP1 (TAP1 Products )
Synonyms
ABC17 antibody, ABCB2 antibody, APT1 antibody, D6S114E antibody, PSF-1 antibody, PSF1 antibody, RING4 antibody, TAP1*0102N antibody, TAP1N antibody, abc17 antibody, abcb2 antibody, apt1 antibody, psf1 antibody, ring4 antibody, tap1a antibody, tap1n antibody, Abcb2 antibody, Ham-1 antibody, Ham1 antibody, MTP1 antibody, TAP antibody, Tap-1 antibody, Y3 antibody, Cim antibody, transporter 1, ATP binding cassette subfamily B member antibody, transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) L homeolog antibody, transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) antibody, TAP1 antibody, tap1.L antibody, Tap1 antibody
Background
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene.,TAP1,ABC17,ABCB2,APT1,D6S114E,PSF-1,PSF1,RING4,TAP1*0102N,TAP1N,Signal Transduction,TAP1
Molecular Weight
87 kDa
Gene ID
6890
UniProt
Q03518
Pathways
Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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