SUFUH antibody (AA 325-484)
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- Target See all SUFUH Antibodies
- SUFUH (Suppressor of Fused Homolog (SUFUH))
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Binding Specificity
- AA 325-484
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SUFUH antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- PPINPQRQNG LAHDRAPSRK DSLESDSSTA IIPHELIRTR QLESVHLKFN QESGALIPLC LRGRLLHGRH FTYKSITGDM AITFVSTGVE GAFATEEHPY AAHGPWLQIL LTEEFVEKML EDLEDLTSPE EFKLPKEYSW PEKKLKVSIL PDVVFDSPLH
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 325-484 of human SUFU (NP_057253.2).
- Isotype
- IgG
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- SUFUH (Suppressor of Fused Homolog (SUFUH))
- Alternative Name
- SUFU (SUFUH Products)
- Background
- The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.,SUFU,PRO1280,SUFUH,SUFUXL,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,Hedgehog Signaling Pathway,SUFU
- Molecular Weight
- 47 kDa/52 kDa/53 kDa
- Gene ID
- 51684
- UniProt
- Q9UMX1
- Pathways
- Hedgehog Signaling, Tube Formation, Maintenance of Protein Location
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