STIP1 antibody (AA 1-300)

Catalog No. ABIN6148592

Product Details anti-STIP1 Antibody

Target: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Binding Specificity: AA 1-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STIP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequence: MEQVNELKEK GNKALSVGNI DDALQCYSEA IKLDPHNHVL YSNRSAAYAK KGDYQKAYED GCKTVDLKPD WGKGYSRKAA ALEFLNRFEE AKRTYEEGLK HEANNPQLKE GLQNMEARLA ERKFMNPFNM PNLYQKLESD PRTRTLLSDP TYRELIEQLR NKPSDLGTKL QDPRIMTTLS VLLGVDLGSM DEEEEIATPP PPPPPKKETK PEPMEEDLPE NKKQALKEKE LGNDAYKKKD FDTALKHYDK AKELDPTNMT YITNQAAVYF EKGDYNKCRE LCEKAIEVGR ENREDYRQIA

Cross-Reactivity: Human, Monkey, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human STIP1 (NP_006810.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:20 - 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for STIP1

Target: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Alternative Name: STIP1 (STIP1 Products)

Synonyms: HOP antibody, IEF-SSP-3521 antibody, P60 antibody, STI1 antibody, STI1L antibody, Hop antibody, Sti1 antibody, p60 antibody, MGC53256 antibody, stip1 antibody, MGC76181 antibody, MGC82554 antibody, zgc:92133 antibody, stress induced phosphoprotein 1 antibody, stress-induced phosphoprotein 1 antibody, stress induced phosphoprotein 1 L homeolog antibody, Stress-induced-phosphoprotein 1 antibody, stress-induced-phosphoprotein 1 antibody, stress induced phosphoprotein 1 S homeolog antibody, STIP1 antibody, Stip1 antibody, stip1.L antibody, GL50803_27310 antibody, PGTG_06468 antibody, stip1 antibody, stip1.S antibody

Background: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A, MIM 140550) and HSP90 (see HSP90AA1, MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009],STIP1,HEL-S-94n,HOP,IEF-SSP-3521,P60,STI1,STI1L,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Neuroscience,Neurodegenerative Diseases,STIP1

Molecular Weight: 59 kDa/62 kDa/68 kDa

Gene ID: 10963

UniProt: P31948