Double-stranded RNA-binding protein Staufen homolog 2 (STAU2) (AA 300-400) antibody

Catalog No. ABIN6148583

Product Details

Target: Double-stranded RNA-binding protein Staufen homolog 2 (STAU2)

Binding Specificity: AA 300-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: PEYGQGMNPI SRLAQIQQAK KEKEPDYVLL SERGMPRRRE FVMQVKVGNE VATGTGPNKK IAKKNAAEAM LLQLGYKAST NLQDQLEKTG ENKGWSGPKP G

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300-400 of human STAU2 (NP_001157852.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details

Target: Double-stranded RNA-binding protein Staufen homolog 2 (STAU2)

Alternative Name: STAU2 (STAU2 Products)

Synonyms: r-staufen protein antibody, staufen (RNA binding protein) homolog 2 (Drosophila) antibody, staufen double-stranded RNA binding protein 2 antibody, Stau2 antibody

Background: Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5 % and 59.9 % similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene.,STAU2,39K2,39K3,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Cell Adhesion,Microtubules,Neuroscience,STAU2

Molecular Weight: 11 kDa/34 kDa/43 kDa/52 kDa/55 kDa/59 kDa/62 kDa

Gene ID: 27067

UniProt: Q9NUL3