ST14 antibody (AA 566-855)

Catalog No. ABIN6148517

Product Details anti-ST14 Antibody

Target: ST14 (Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14))

Binding Specificity: AA 566-855

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST14 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TCTKHTYRCL NGLCLSKGNP ECDGKEDCSD GSDEKDCDCG LRSFTRQARV VGGTDADEGE WPWQVSLHAL GQGHICGASL ISPNWLVSAA HCYIDDRGFR YSDPTQWTAF LGLHDQSQRS APGVQERRLK RIISHPFFND FTFDYDIALL ELEKPAEYSS MVRPICLPDA SHVFPAGKAI WVTGWGHTQY GGTGALILQK GEIRVINQTT CENLLPQQIT PRMMCVGFLS GGVDSCQGDS GGPLSSVEAD GRIFQAGVVS WGDGCAQRNK PGVYTRLPLF RDWIKENTGV

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 566-855 of human ST14 (NP_068813.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ST14

Target: ST14 (Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14))

Alternative Name: ST14 (ST14 Products)

Background: The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.,ST14,ARCI11,HAI,MT-SP1,MTSP1,PRSS14,SNC19,TADG15,TMPRSS14,ST14

Molecular Weight: 94 kDa

Gene ID: 6768

UniProt: Q9Y5Y6