SSX4 antibody (AA 70-188)

Catalog No. ABIN6148508

Product Details anti-SSX4 Antibody

Target: SSX4 (Synovial Sarcoma, X Breakpoint 4 (SSX4))

Binding Specificity: AA 70-188

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSX4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FMRSKRAADF HGNDFGNDRN HRNQVERPQM TFGSLQRIFP KIMPKKPAEE ENGLKEVPEA SGPQNDGKQL CPPGNPSTLE KINKTSGPKR GKHAWTHRLR ERKQLVVYEE ISDPEEDDE

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 70-188 of human SSX4 (NP_005627.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SSX4

Target: SSX4 (Synovial Sarcoma, X Breakpoint 4 (SSX4))

Alternative Name: SSX4 (SSX4 Products)

Synonyms: CT5.4 antibody, SSX family member 4 antibody, SSX4 antibody

Background: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.,SSX4,CT5.4,SSX4

Molecular Weight: 17 kDa/21 kDa

Gene ID: 6759

UniProt: O60224