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SPSB1 antibody
SPSB1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SPSB1 Antibody
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Target
See all SPSB1 Antibodies
SPSB1
(SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1))
Reactivity
All reactivities for SPSB1 antibodies
Human
Host
All hosts for SPSB1 antibodies
Rabbit
Clonality
All clonalities for SPSB1 antibodies
Polyclonal
Conjugate
All conjugates for SPSB1 antibodies
This SPSB1 antibody is un-conjugated
Application
All applications for SPSB1 antibodies
Western Blotting (WB)
Cross-Reactivity
Human, Mouse
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant protein of human SPSB1
Isotype
IgG
Top Product
Discover our top product SPSB1 Primary Antibody
Alternatives
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anti-SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1) (AA 95-144) antibody
SPSB1
Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Chicken, Monkey, Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for SPSB1
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Target
SPSB1
(SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1))
Alternative Name
SPSB1 (SPSB1 Products )
Synonyms
SSB-1 antibody, SSB1 antibody, 1110014L01Rik antibody, 4930422J18Rik antibody, AI596360 antibody, AI854583 antibody, splA/ryanodine receptor domain and SOCS box containing 1 antibody, SPSB1 antibody, Spsb1 antibody
Background
Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Negatively regulates nitric oxide (NO production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2. Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5.,SPSB1,SSB-1,SSB1,SPSB1
Molecular Weight
30 kDa
Gene ID
80176
UniProt
Q96BD6
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