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SPAG8 antibody (AA 220-420)

SPAG8 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6148323
  • Target See all SPAG8 Antibodies
    SPAG8 (Sperm Associated Antigen 8 (SPAG8))
    Binding Specificity
    • 15
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 220-420
    Reactivity
    • 54
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 51
    • 4
    Rabbit
    Clonality
    • 53
    • 2
    Polyclonal
    Conjugate
    • 21
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPAG8 antibody is un-conjugated
    Application
    • 29
    • 23
    • 13
    • 13
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    LVADRVPNYT SWSQHCPWEP QKQPPWEFLQ VLEPGARGLW KPPDIKGKLM VCYETLPRGQ CLLYNWEEER ATNHLDQVPS MQDGSESFFF RHGHRGLLTM QLKSPMPSST TQKDSYQPPG NVYWPLRGKR EAMLEMLLQH QICKEVQAEQ EPTRKLFEVE SVTHHDYRME LAQAGTPAPT KPHDYRQEQP ETFWIQRAPQ L
    Cross-Reactivity
    Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human SPAG8 (NP_758516.1).
    Isotype
    IgG
    Top Product
    Discover our top product SPAG8 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SPAG8 (Sperm Associated Antigen 8 (SPAG8))
    Alternative Name
    SPAG8 (SPAG8 Products)
    Synonyms
    BS-84 antibody, HSD-1 antibody, SMP1 antibody, SPAG3 antibody, hSMP-1 antibody, MH-SPAG8 antibody, sperm associated antigen 8 antibody, SPAG8 antibody, Spag8 antibody
    Background
    The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. This protein interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator)-ACT-mediated gene transcription during spermatogenesis. This protein may also play a role in spermatogenesis by regulating microtubule formation and cell division. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.,SPAG8,BS-84,CILD28,CT142,HSD-1,SMP1,SPAG3,hSMP-1,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Stem Cells,Germline Stem Cells,SPAG8
    Molecular Weight
    44 kDa/51 kDa/53 kDa
    Gene ID
    26206
    UniProt
    Q99932
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