SOX30 antibody (AA 1-150)

Catalog No. ABIN6148300

Product Details anti-SOX30 Antibody

Target: SOX30 (SRY (Sex Determining Region Y)-Box 30 (SOX30))

Binding Specificity: AA 1-150

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX30 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MERARPEPPP PPPPPPRQPP RPTPPRPLRP APPAQPVEAA TFRAAAAERS QSPSAQATAA MAAVASSCGE AAAAGAQAAG TRRLLQVKPE QVLLLPPGGP GVPPAPDEGA AAAAAAAAAA ASSAQARLLQ LRPELLLLPP QSAADGGPCR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of mouse SOX30 (NP_775560.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-SOX30 antibody (ABIN6148300)

Chen, Zheng, Gao, Lin, Yang, Wang, Wang, Xie, Hua, Liu, Sha, Griswold, Li, Tang, Tong: "Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis." in: Cell research, Vol. 28, Issue 9, pp. 879-896, (2018) (PubMed).

Bai, Fu, Yin, Cui, Yue, Li, Cheng, Tan, Liu, Guo, Zhang, Xie, He, Wang, Feng, Xin, Zhang, Lin, Shen, Sun, Guo, Zheng, Ye: "Sox30 initiates transcription of haploid genes during late meiosis and spermiogenesis in mouse testes." in: Development (Cambridge, England), Vol. 145, Issue 13, (2018) (PubMed).

Target Details for SOX30

Target: SOX30 (SRY (Sex Determining Region Y)-Box 30 (SOX30))

Alternative Name: SOX30 (SOX30 Products)

Synonyms: SOX30 antibody, SRY-box 30 antibody, SRY (sex determining region Y)-box 30 antibody, SRY box 30 antibody, Sox30 protein antibody, SOX30 antibody, Sox30 antibody, sox30 antibody

Background: This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein acts as a transcriptional regulator when present in a complex with other proteins. It can activate p53 transcription to promote tumor cell apoptosis in lung cancer. The protein may be involved in the differentiation of developing male germ cells. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 5.,SOX30,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Stem Cells,Germline Stem Cells,SOX30

Molecular Weight: 83 kDa

Gene ID: 214105

UniProt: Q8CGW4