SNRNP200 antibody (AA 1947-2136)

Catalog No. ABIN6148204

Product Details anti-SNRNP200 Antibody

Target: SNRNP200 (Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200))

Binding Specificity: AA 1947-2136

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNRNP200 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QMVTQAMWSK DSYLKQLPHF TSEHIKRCTD KGVESVFDIM EMEDEERNAL LQLTDSQIAD VARFCNRYPN IELSYEVVDK DSIRSGGPVV VLVQLEREEE VTGPVIAPLF PQKREEGWWV VIGDAKSNSL ISIKRLTLQQ KAKVKLDFVA PATGAHNYTL YFMSDAYMGC DQEYKFSVDV KEAETDSDSD

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1947-2136 of human SNRNP200 (NP_054733.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SNRNP200

Target: SNRNP200 (Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200))

Alternative Name: SNRNP200 (SNRNP200 Products)

Synonyms: ASCC3L1 antibody, BRR2 antibody, HELIC2 antibody, RP33 antibody, U5-200KD antibody, small nuclear ribonucleoprotein U5 subunit 200 antibody, SNRNP200 antibody

Background: Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.,SNRNP200,ASCC3L1,BRR2,HELIC2,RP33,U5-200KD,SNRNP200,Epigenetics & Nuclear Signaling,RNA Binding,SNRNP200

Molecular Weight: 71 kDa/244 kDa

Gene ID: 23020

UniProt: O75643

Pathways: Ribonucleoprotein Complex Subunit Organization