SNAPIN antibody (AA 1-136)

Catalog No. ABIN6148187

Product Details anti-SNAPIN Antibody

Target: SNAPIN (SNAP-Associated Protein (SNAPIN))

Binding Specificity: AA 1-136

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAPIN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MAGAGSAAVS GAGTPVAGPT GRDLFAEGLL EFLRPAVQQL DSHVHAVRES QVELREQIDN LATELCRINE DQKVALDLDP YVKKLLNARR RVVLVNNILQ NAQERLRRLN HSVAKETARR RAMLDSGIYP PGSPGK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human SNAPIN (NP_036569.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SNAPIN

Target: SNAPIN (SNAP-Associated Protein (SNAPIN))

Alternative Name: SNAPIN (SNAPIN Products)

Background: The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.,SNAPIN,BLOC1S7,BLOS7,BORCS3,SNAPAP,Signal Transduction,Neuroscience,Cell Type Marker,Neuron marker,Synapse marker,SNAPIN

Molecular Weight: 14 kDa

Gene ID: 23557

UniProt: O95295

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis