SMAD7 antibody (AA 220-390)
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- Target See all SMAD7 Antibodies
- SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
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Binding Specificity
- AA 220-390
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SMAD7 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KPTADCPDAV PSSAETGGTN YLAPGGLSDS QLLLEPGDRS HWCVVAYWEE KTRVGRLYCV QEPSLDIFYD LPQGNGFCLG QLNSDNKSQL VQKVRSKIGC GIQLTREVDG VWVYNRSSYP IFIKSATLDN PDSRTLLVHK VFPGFSIKAF DYEKAYSLQR PNDHEFMQQP W
- Cross-Reactivity
- Human
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 220-390 of human Smad7 (NP_005895.1).
- Isotype
- IgG
- Top Product
- Discover our top product SMAD7 Primary Antibody
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anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 1-100) antibody
SMAD7 Reactivity: Human, Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), FACS Host: Rabbit Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibodySMAD7 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 1G10 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibodySMAD7 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 3E9 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 195-224) antibodySMAD7 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 195-224) antibodySMAD7 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB18598 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibodySMAD7 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 4C11 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 302-400) antibodySMAD7 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 3A11 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 36-247) antibodySMAD7 Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (N-Term) antibodySMAD7 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibodySMAD7 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
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- Application Notes
- WB,1:500 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
- Alternative Name
- SMAD7 (SMAD7 Products)
- Background
- The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.,SMAD7,CRCS3,MADH7,MADH8,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,TGF-b-Smad Signaling Pathway,SMADs,SMAD7
- Molecular Weight
- 23 kDa/46 kDa
- Gene ID
- 4092
- UniProt
- O15105
- Pathways
- Interferon-gamma Pathway, Cell-Cell Junction Organization
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