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SIRT6 antibody (C-Term)

SIRT6 Reactivity: Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6147800
  • Target See all SIRT6 Antibodies
    SIRT6 (Sirtuin 6 (SIRT6))
    Binding Specificity
    • 15
    • 15
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 89
    • 30
    • 16
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 83
    • 13
    • 2
    Rabbit
    Clonality
    • 80
    • 18
    Polyclonal
    Conjugate
    • 50
    • 11
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIRT6 antibody is un-conjugated
    Application
    • 79
    • 38
    • 33
    • 14
    • 14
    • 10
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    NLQPTKHDRQ ADLRIHGYVD EVMCRLMKHL GLEIPAWDGP CVLDKALPPL PRPVALKAEP PVHLNGAVHV SYKSKPNSPI LHRPPKRVKT EAAPS
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of mouse SIRT6 (NP_001156902.1).
    Isotype
    IgG
    Top Product
    Discover our top product SIRT6 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Zhu, Yan, Shao, Tian, Zhou: "Downregulation of SIRT6 is associated with poor prognosis in patients with non-small cell lung cancer." in: The Journal of international medical research, Vol. 46, Issue 4, pp. 1517-1527, (2018) (PubMed).

  • Target
    SIRT6 (Sirtuin 6 (SIRT6))
    Alternative Name
    SIRT6 (SIRT6 Products)
    Synonyms
    2810449N18Rik antibody, AI043036 antibody, Sir2l6 antibody, SIR2L6 antibody, zgc:86729 antibody, sirtuin 6 antibody, sirtuin 6 S homeolog antibody, Sirt6 antibody, SIRT6 antibody, sirt6.S antibody, sirt6 antibody
    Background
    This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.,SIRT6,SIR2L6,sirtuin 6,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Deacetylation,SIRT6
    Molecular Weight
    36 kDa/39 kDa
    Gene ID
    50721
    UniProt
    Q8N6T7
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