SGCD antibody (AA 61-290)

Catalog No. ABIN6147700

Product Details anti-SGCD Antibody

Target: SGCD (Sarcoglycan, delta (35kDa Dystrophin-Associated Glycoprotein) (SGCD))

Binding Specificity: AA 61-290

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGCD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: NFTIDGMGNL RITEKGLKLE GDSEFLQPLY AKEIQSRPGN ALYFKSARNV TVNILNDQTK VLTQLITGPK AVEAYGKKFE VKTVSGKLLF SADNNEVVVG AERLRVLGAE GTVFPKSIET PNVRADPFKE LRLESPTRSL VMEAPKGVEI NAEAGNMEAT CRTELRLESK DGEIKLDAAK IRLPRLPHGS YTPTGTRQKV FEICVCANGR LFLSQAGAGS TCQINTSVCL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 61-290 of human Delta-sarcoglycan (Delta-sarcoglycan (SGCD)) (NP_000328.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SGCD

Target: SGCD (Sarcoglycan, delta (35kDa Dystrophin-Associated Glycoprotein) (SGCD))

Alternative Name: SGCD (SGCD Products)

Background: The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.,SGCD,35DAG,CMD1L,DAGD,SG-delta,SGCDP,SGD,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,SGCD

Molecular Weight: 28 kDa/32 kDa

Gene ID: 6444

UniProt: Q92629

Pathways: Maintenance of Protein Location