AGR3 antibody

Catalog No. ABIN614768

Product Details anti-AGR3 Antibody

Target: AGR3 (Anterior Gradient 3 (AGR3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AGR3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody recognizes the epitope HETTDKNLS within the AGR3 (AG3) protein (19-20 kDa), a secreted cytoplasmic protein which can serve as a marker of carcinogenesis.

Purification: Affinity Chromatography on Protein A

Immunogen: Purified Human AGR3 protein.

Clone: AGR3-1

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, 15 mM Sodium Azide, 0.2 % (w/v) high-grade protease free BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for AGR3

Target: AGR3 (Anterior Gradient 3 (AGR3))

Alternative Name: AGR3 (AGR3 Products)

Synonyms: AG3 antibody, BCMP11 antibody, HAG3 antibody, PDIA18 antibody, hAG-3 antibody, E030025L21Rik antibody, Gm888 antibody, RGD1565406 antibody, anterior gradient 3, protein disulphide isomerase family member antibody, anterior gradient 3 antibody, AGR3 antibody, Agr3 antibody

Background: AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG-3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.Synonyms: Anterior gradient protein 3 homolog, BCMP11, HAG-3, HAG3, breast cancer membrane protein 11

Gene ID: 155465, 9606

UniProt: Q8TD06