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SF3B3 antibody (AA 948-1217)
SF3B3
Reactivity: Human
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SF3B3 Antibody
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Target
See all SF3B3 Antibodies
SF3B3
(Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
Binding Specificity
All epitopes for SF3B3 antibodies
AA 948-1217
Reactivity
All reactivities for SF3B3 antibodies
Human
Host
All hosts for SF3B3 antibodies
Rabbit
Clonality
All clonalities for SF3B3 antibodies
Polyclonal
Conjugate
All conjugates for SF3B3 antibodies
This SF3B3 antibody is un-conjugated
Application
All applications for SF3B3 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Sequence
VPAAIAPFQG RVLIGVGKLL RVYDLGKKKL LRKCENKHIA NYISGIQTIG HRVIVSDVQE SFIWVRYKRN ENQLIIFADD TYPRWVTTAS LLDYDTVAGA DKFGNICVVR LPPNTNDEVD EDPTGNKALW DRGLLNGASQ KAEVIMNYHV GETVLSLQKT TLIPGGSESL VYTTLSGGIG ILVPFTSHED HDFFQHVEMH LRSEHPPLCG RDHLSFRSYY FPVKNVIDGD LCEQFNSMEP NKQKNVSEEL DRTPPEVSKK LEDIRTRYAF
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 948-1217 of human SF3B3/SAP130 (NP_036558.3).
Isotype
IgG
Top Product
Discover our top product SF3B3 Primary Antibody
Alternatives
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anti-Splicing Factor 3b, Subunit 3, 130kDa (SF3B3) (Middle Region) antibody
SF3B3
Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for SF3B3
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Target
SF3B3
(Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
Alternative Name
SF3B3 (SF3B3 Products )
Synonyms
GB11574 antibody, rse1 antibody, sap130 antibody, sf3b130 antibody, staf130 antibody, sf3b3 antibody, 1810061H24Rik antibody, 5730409A01Rik antibody, AA409318 antibody, D8Ertd633e antibody, RSE1 antibody, SAP130 antibody, mKIAA0017 antibody, ik:tdsubc_2b2 antibody, wu:fb81f05 antibody, xx:tdsubc_2b2 antibody, zgc:55440 antibody, SF3b130 antibody, STAF130 antibody, splicing factor 3b subunit 3 antibody, splicing factor 3B subunit 3 antibody, splicing factor 3b, subunit 3, 130kDa antibody, splicing factor 3b subunit 3 L homeolog antibody, splicing factor 3b, subunit 3 antibody, SF3B3 antibody, LOC550935 antibody, sf3b3 antibody, Sf3b3 antibody, LOC100178056 antibody, sf3b3.L antibody
Background
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.,SF3B3,RSE1,SAP130,SF3b130,STAF130,Epigenetics & Nuclear Signaling,Transcription Factors,SF3B3
Molecular Weight
30 kDa/44 kDa/135 kDa
Gene ID
23450
UniProt
Q15393
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