SET/TAF-I antibody (AA 1-277)

Catalog No. ABIN6147631

Product Details anti-SET/TAF-I Antibody

Target: SET/TAF-I (SET) (SET Nuclear Oncogene (SET))

Binding Specificity: AA 1-277

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SET/TAF-I antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: MSAPAAKVSK KELNSNHDGA DETSEKEQQE AIEHIDEVQN EIDRLNEQAS EEILKVEQKY NKLRQPFFQK RSELIAKIPN FWVTTFVNHP QVSALLGEED EEALHYLTRV EVTEFEDIKS GYRIDFYFDE NPYFENKVLS KEFHLNESGD PSSKSTEIKW KSGKDLTKRS SQTQNKASRK RQHEEPESFF TWFTDHSDAG ADELGEVIKD DIWPNPLQYY LVPDMDDEEG EGEEDDDDDE EEEGLEDIDE EGDEDEGEED EDDDEGEEGE EDEGEDD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human SET/TAF1 (NP_003002.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SET/TAF-I

Target: SET/TAF-I (SET) (SET Nuclear Oncogene (SET))

Alternative Name: SET (SET Products)

Synonyms: 2PP2A antibody, I2PP2A antibody, IGAAD antibody, IPP2A2 antibody, PHAPII antibody, TAF-I antibody, TAF-IBETA antibody, 2610030F17Rik antibody, 5730420M11Rik antibody, AA407739 antibody, I-2PP2A antibody, StF-IT-1 antibody, 2pp2a antibody, i2pp2a antibody, igaad antibody, ipp2a2 antibody, phapii antibody, set antibody, set-a antibody, set-b antibody, taf-ibeta antibody, wu:fb30g11 antibody, wu:fd16c08 antibody, SET nuclear proto-oncogene antibody, SET nuclear oncogene antibody, SET translocation antibody, SET nuclear proto-oncogene L homeolog antibody, SET nuclear proto-oncogene b antibody, SET antibody, Set antibody, LOC403555 antibody, set.L antibody, setb antibody

Background: The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.,SET,2PP2A,I2PP2A,IGAAD,IPP2A2,PHAPII,TAF-I,TAF-IBETA,Epigenetics & Nuclear Signaling,Chromatin Remodeling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Immunology & Inflammation,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,SET

Molecular Weight: 30 kDa/31 kDa/32 kDa/33 kDa

Gene ID: 6418

UniProt: Q01105

Pathways: Apoptosis