SERPINA7 antibody (AA 146-415)

Catalog No. ABIN6147581

Product Details anti-SERPINA7 Antibody

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Binding Specificity: AA 146-415

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINA7 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: FLNDVKTLYE TEVFSTDFSN ISAAKQEINS HVEMQTKGKV VGLIQDLKPN TIMVLVNYIH FKAQWANPFD PSKTEDSSSF LIDKTTTVQV PMMHQMEQYY HLVDMELNCT VLQMDYSKNA LALFVLPKEG QMESVEAAMS SKTLKKWNRL LQKGWVDLFV PKFSISATYD LGATLLKMGI QHAYSENADF SGLTEDNGLK LSNAAHKAVL HIGEKGTEAA AVPEVELSDQ PENTFLHPII QIDRSFMLLI LERSTRSILF LGKVVNPTEA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 146-415 of human SERPINA7 (NP_000345.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SERPINA7

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Alternative Name: SERPINA7 (SERPINA7 Products)

Synonyms: C730040N12Rik antibody, Tbg antibody, TBG antibody, THYROXINE-BINDING GLOBULIN antibody, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 antibody, serpin family A member 7 antibody, Serpina7 antibody, SERPINA7 antibody

Background: There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.,SERPINA7,TBG,TBGQTL,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,SERPINA7

Molecular Weight: 46 kDa

Gene ID: 6906

UniProt: P05543

Pathways: Hormone Transport