SCO2 antibody (AA 1-130)

Catalog No. ABIN6147457

Product Details anti-SCO2 Antibody

Target: SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))

Binding Specificity: AA 1-130

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCO2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MLLLTRSPTA WHRLSQLKPR VLPGTLGGQA LHLRSWLLSR QGPAETGGQG QPQGPGLRTR LLITGLFGAG LGGAWLALRA EKERLQQQKR TEALRQAAVG QGDFHLLDHR GRARCKADFR GQWVLMYFGF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human SCO2 (NP_001162582.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SCO2

Target: SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))

Alternative Name: SCO2 (SCO2 Products)

Synonyms: CEMCOX1 antibody, MYP6 antibody, SCO1L antibody, SCO cytochrome oxidase deficient homolog 2 (yeast) antibody, SCO2 cytochrome c oxidase assembly protein antibody, SCO2, cytochrome c oxidase assembly protein antibody, SCO2 antibody, Sco2 antibody

Background: Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors, this gene encodes one of the COX assembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy and myopia 6.,SCO2,CEMCOX1,MYP6,SCO1L,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Oxidative phosphorylation,SCO2

Molecular Weight: 29 kDa

Gene ID: 9997

UniProt: O43819

Pathways: Transition Metal Ion Homeostasis, Warburg Effect