RNF8 antibody (AA 1-260)
-
- Target See all RNF8 Antibodies
- RNF8 (Ring Finger Protein 8 (RNF8))
-
Binding Specificity
- AA 1-260
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This RNF8 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunofluorescence (IF)
- Sequence
- MGEPGFFVTG DRAGGRSWCL RRVGMSAGWL LLEDGCEVTV GRGFGVTYQL VSKICPLMIS RNHCVLKQNP EGQWTIMDNK SLNGVWLNRA RLEPLRVYSI HQGDYIQLGV PLENKENAEY EYEVTEEDWE TIYPCLSPKN DQMIEKNKEL RTKRKFSLDE LAGPGAEGPS NLKSKINKVS CESGQPVKSQ GKGEVASTPS DNLDPKLTAL EPSKTTGAPI YPGFPKVTEV HHEQKASNSS ASQRSLQMFK VTMSRILRLK
- Cross-Reactivity
- Human
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human RNF8 (NP_003949.1).
- Isotype
- IgG
- Top Product
- Discover our top product RNF8 Primary Antibody
-
-
- Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- RNF8 (Ring Finger Protein 8 (RNF8))
- Alternative Name
- RNF8 (RNF8 Products)
- Background
- The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants.,RNF8,hRNF8,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,RNF8
- Molecular Weight
- 10 kDa/50 kDa/55 kDa
- Gene ID
- 9025
- UniProt
- O76064
- Pathways
- Production of Molecular Mediator of Immune Response
-