RNF7 antibody (AA 1-113)

Catalog No. ABIN6147047

Product Details anti-RNF7 Antibody

Target: RNF7 (Ring Finger Protein 7 (RNF7))

Binding Specificity: AA 1-113

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF7 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: MADVEDGEET CALASHSGSS GSKSGGDKMF SLKKWNAVAM WSWDVECDTC AICRVQVMDA CLRCQAENKQ EDCVVVWGEC NHSFHNCCMS LWVKQNNRCP LCQQDWVVQR IGK

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human RNF7 (NP_055060.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:20 - 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RNF7

Target: RNF7 (Ring Finger Protein 7 (RNF7))

Alternative Name: RNF7 (RNF7 Products)

Synonyms: CKBBP1 antibody, ROC2 antibody, SAG antibody, Rbx2 antibody, ring finger protein 7 antibody, RNF7 antibody, Rnf7 antibody

Background: The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.,RNF7,CKBBP1,ROC2,SAG,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Endocrine & Metabolism,RNF7

Molecular Weight: 9 kDa/10 kDa/11 kDa/12 kDa

Gene ID: 9616

UniProt: Q9UBF6

Pathways: Positive Regulation of Endopeptidase Activity