RFC4 antibody (AA 204-363)
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- Target See all RFC4 Antibodies
- RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))
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Binding Specificity
- AA 204-363
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RFC4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
- Sequence
- DKIQQQRLLD IAKKENVKIS DEGIAYLVKV SEGDLRKAIT FLQSATRLTG GKEITEKVIT DIAGVIPAEK IDGVFAACQS GSFDKLEAVV KDLIDEGHAA TQLVNQLHDV VVENNLSDKQ KSIITEKLAE VDKCLADGAD EHLQLISLCA TVMQQLSQNC
- Cross-Reactivity
- Human, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 204-363 of human RFC4 (NP_002907.1).
- Isotype
- IgG
- Top Product
- Discover our top product RFC4 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:100,IP,1:50 - 1:200
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))
- Alternative Name
- RFC4 (RFC4 Products)
- Synonyms
- 44.t00003 antibody, 21.m03053 antibody, rfc4 antibody, A1 antibody, AI894123 antibody, AU040575 antibody, RFC37 antibody, rfc2 antibody, replication factor C subunit 4 antibody, Replication factor C subunit 4 antibody, replication factor C (activator 1) 4 antibody, replication factor C subunit 4 L homeolog antibody, PFL2005w antibody, EHI_167150 antibody, TP03_0432 antibody, Tb11.01.1310 antibody, BBOV_IV002210 antibody, rfc4 antibody, rfc-4 antibody, Rfc4 antibody, RFC4 antibody, rfc4.L antibody
- Background
- The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.,RFC4,A1,RFC37,Epigenetics & Nuclear Signaling,RFC4
- Molecular Weight
- 33 kDa/39 kDa
- Gene ID
- 5984
- UniProt
- P35249
- Pathways
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
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