REG4 antibody (AA 23-158)

Catalog No. ABIN6146859

Product Details anti-REG4 Antibody

Target: REG4 (Regenerating Islet-Derived Family, Member 4 (REG4))

Binding Specificity: AA 23-158

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REG4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DIIMRPSCAP GWFYHKSNCY GYFRKLRNWS DAELECQSYG NGAHLASILS LKEASTIAEY ISGYQRSQPI WIGLHDPQKR QQWQWIDGAM YLYRSWSGKS MGGNKHCAEM SSNNNFLTWS SNECNKRQHF LCKYRP

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-158 of human REG4 (NP_114433.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for REG4

Target: REG4 (Regenerating Islet-Derived Family, Member 4 (REG4))

Alternative Name: REG4 (REG4 Products)

Synonyms: GISP antibody, REG-IV antibody, RELP antibody, 2010002L15Rik antibody, regenerating family member 4 antibody, regenerating islet-derived family, member 4 antibody, Reg4 antibody, REG4 antibody

Background: Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.,REG4,GISP,REG-IV,RELP,REG4

Molecular Weight: 14 kDa/18 kDa

Gene ID: 83998

UniProt: Q9BYZ8