RAB35 antibody (AA 1-201)

Catalog No. ABIN6146576

Product Details anti-RAB35 Antibody

Target: RAB35 (RAB35, Member RAS Oncogene Family (RAB35))

Binding Specificity: AA 1-201

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB35 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: MARDYDHLFK LLIIGDSGVG KSSLLLRFAD NTFSGSYITT IGVDFKIRTV EINGEKVKLQ IWDTAGQERF RTITSTYYRG THGVIVVYDV TSAESFVNVK RWLHEINQNC DDVCRILVGN KNDDPERKVV ETEDAYKFAG QMGIQLFETS AKENVNVEEM FNCITELVLR AKKDNLAKQQ QQQQNDVVKL TKNSKRKKRC C

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human RAB35 (NP_006852.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-RAB35 antibody (ABIN6146576)

Bei, Xu, Lv, Yu, Xu, Che, Das, Tigges, Toxavidis, Ghiran, Shah, Li, Zhang, Das, Xiao: "Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury." in: Basic research in cardiology, Vol. 112, Issue 4, pp. 38, (2018) (PubMed).

Deng, Wang, Gu, Duan, Cui, Zhang, Chen, Sun, Dong, Du: "MICAL1 controls cell invasive phenotype via regulating oxidative stress in breast cancer cells." in: BMC cancer, Vol. 16, pp. 489, (2017) (PubMed).

Target Details for RAB35

Target: RAB35 (RAB35, Member RAS Oncogene Family (RAB35))

Alternative Name: RAB35 (RAB35 Products)

Synonyms: h-ray antibody, rab1c antibody, MGC69101 antibody, ray antibody, MGC76044 antibody, dZ146N9.2 antibody, zgc:100812 antibody, si:busm1-146n9.2 antibody, H-ray antibody, RAB1C antibody, RAY antibody, 9530019H02Rik antibody, AU040256 antibody, RAB35, member RAS oncogene family S homeolog antibody, RAB35, member RAS oncogene family antibody, RAB35, member RAS oncogene family b antibody, rab35.S antibody, rab35 antibody, rab35b antibody, RAB35 antibody, Rab35 antibody

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2 and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth. Together with TBC1D13 may be involved in regulation of insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane in adipocytes.,RAB35,H-ray,RAB1C,RAY,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Immunology & Inflammation,Cytokines,RAB35

Molecular Weight: 17 kDa/23 kDa

Gene ID: 11021

UniProt: Q15286