PTS antibody (AA 1-145)

Catalog No. ABIN6146483

Product Details anti-PTS Antibody

Target: PTS (6-Pyruvoyltetrahydropterin Synthase (PTS))

Binding Specificity: AA 1-145

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTS antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: MSTEGGGRRC QAQVSRRISF SASHRLYSKF LSDEENLKLF GKCNNPNGHG HNYKVVVTVH GEIDPATGMV MNLADLKKYM EEAIMQPLDH KNLDMDVPYF ADVVSTTENV AVYIWDNLQK VLPVGVLYKV KVYETDNNIV VYKGE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human PTS (NP_000308.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:10 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PTS

Target: PTS (6-Pyruvoyltetrahydropterin Synthase (PTS))

Alternative Name: PTS (PTS Products)

Background: The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia.,PTS,PTPS,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Neuroscience,PTS

Molecular Weight: 16 kDa

Gene ID: 5805

UniProt: Q03393