PSPC1 antibody (AA 1-70)

Catalog No. ABIN6146363

Product Details anti-PSPC1 Antibody

Target: PSPC1 (Paraspeckle Component 1 (PSPC1))

Binding Specificity: AA 1-70

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSPC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Sequence: MMLRGNLKQV RIEKNPARLR ALESAVGESE PAAAAAMALA LAGEPAPPAP APPEDHPDEE MGFTIDIKSF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human PSPC1 (NP_001035879.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PSPC1

Target: PSPC1 (Paraspeckle Component 1 (PSPC1))

Alternative Name: PSPC1 (PSPC1 Products)

Synonyms: rexp86 antibody, PSP1 antibody, fj85a06 antibody, wu:fj85a06 antibody, zgc:136470 antibody, 5730470C09Rik antibody, AI327109 antibody, AI449052 antibody, paraspeckle component 1 antibody, paraspeckle component 1 L homeolog antibody, paraspeckle protein 1 antibody, PSPC1 antibody, Tsp_01792 antibody, pspc1 antibody, pspc1.L antibody, Pspc1 antibody

Background: This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified.,PSPC1,PSP1,Epigenetics & Nuclear Signaling,RNA Binding,PSPC1

Molecular Weight: 45 kDa/58 kDa

Gene ID: 55269

UniProt: Q8WXF1