PPFIA1 antibody (AA 660-800)

Catalog No. ABIN6146015

Product Details anti-PPFIA1 Antibody

Target: PPFIA1 (Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1))

Binding Specificity: AA 660-800

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPFIA1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IESRVGSGSL DNLGRFRSMS SIPPYPASSL ASSSPPGSGR STPRRIPHSP AREVDRLGVM TLLPPSREEV RDDKTTIKCE TSPPSSPRAL RLDRLHKGAL HTVSHEDIRD IRNSTGSQDG PVSNPSSSNS SQDSLHKAPK K

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 660-800 of human PPFIA1 (NP_003617.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PPFIA1

Target: PPFIA1 (Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1))

Alternative Name: PPFIA1 (PPFIA1 Products)

Synonyms: LIP.1 antibody, LIP1 antibody, LIPRIN antibody, C030014K08Rik antibody, C87158 antibody, PTPRF interacting protein alpha 1 antibody, protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 antibody, PPFIA1 antibody, Ppfia1 antibody

Background: The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described.,PPFIA1,LIP.1,LIP1,LIPRIN,Signal Transduction,Neuroscience,PPFIA1

Molecular Weight: 133 kDa/135 kDa

Gene ID: 8500

UniProt: Q13136