PORCN antibody (AA 220-320)

Catalog No. ABIN6145972

Product Details anti-PORCN Antibody

Target: PORCN (Porcupine Homolog (PORCN))

Binding Specificity: AA 220-320

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PORCN antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PLNGDRLLRN KKRKARWLRA YESAVSFHFS NYFVGFLSEA TATLAGAGFT EEKDHLEWDL TVSKPLNVEL PRSMVEVVTS WNLPMSYWLN NYVFKNALRL G

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 220-320 of human PORCN (NP_982299.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PORCN

Target: PORCN (Porcupine Homolog (PORCN))

Alternative Name: PORCN (PORCN Products)

Background: This gene belongs to the evolutionarily conserved porcupine (Porc) gene family. Genes of the porcupine family encode endoplasmic reticulum proteins with multiple transmembrane domains. Porcupine proteins are involved in the processing of Wnt (wingless and int homologue) proteins. Disruption of this gene is associated with focal dermal hypoplasia, and the encoded protein has been implicated in cancer. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.,PORCN,DHOF,FODH,MG61,PORC,PPN,Stem Cells,PORCN

Molecular Weight: 42 kDa/51 kDa/52 kDa

Gene ID: 64840

UniProt: Q9H237