POLR3B antibody (AA 680-900)

Catalog No. ABIN6145938

Product Details anti-POLR3B Antibody

Target: POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))

Binding Specificity: AA 680-900

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR3B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SPRNTYQCAM GKQAMGTIGY NQRNRIDTLM YLLAYPQKPM VKTKTIELIE FEKLPAGQNA TVAVMSYSGY DIEDALVLNK ASLDRGFGRC LVYKNAKCTL KRYTNQTFDK VMGPMLDAAT RKPIWRHEIL DADGICSPGE KVENKQVLVN KSMPTVTQIP LEGSNVPQQP QYKDVPITYK GATDSYIEKV MISSNAEDAF LIKMLLRQTR RPEIGDKFSS R

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 680-900 of human POLR3B (NP_060552.4).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for POLR3B

Target: POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))

Alternative Name: POLR3B (POLR3B Products)

Background: This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,POLR3B,C128,HLD8,INMAP,RPC2,Epigenetics & Nuclear Signaling,POLR3B

Molecular Weight: 121 kDa/127 kDa

Gene ID: 55703

UniProt: Q9NW08