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POLG2 antibody (AA 216-485)
POLG2
Reactivity: Human
IHC, WB, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-POLG2 Antibody
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Target
See all POLG2 Antibodies
POLG2
(Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))
Binding Specificity
All epitopes for POLG2 antibodies
AA 216-485
Reactivity
All reactivities for POLG2 antibodies
Human
Host
All hosts for POLG2 antibodies
Rabbit
Clonality
All clonalities for POLG2 antibodies
Polyclonal
Conjugate
All conjugates for POLG2 antibodies
This POLG2 antibody is un-conjugated
Application
All applications for POLG2 antibodies
Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
Sequence
HPVFDTKQIR NGVKSIGEKT EASLVWFTPP RTSNQWLDFW LRHRLQWWRK FAMSPSNFSS SDCQDEEGRK GNKLYYNFPW GKELIETLWN LGDHELLHMY PGNVSKLHGR DGRKNVVPCV LSVNGDLDRG MLAYLYDSFQ LTENSFTRKK NLHRKVLKLH PCLAPIKVAL DVGRGPTLEL RQVCQGLFNE LLENGISVWP GYLETMQSSL EQLYSKYDEM SILFTVLVTE TTLENGLIHL RSRDTTMKEM MHISKLKDFL IKYISSAKNV
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 216-485 of human POLG2 (NP_009146.2).
Isotype
IgG
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:10 - 1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for POLG2
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Target
POLG2
(Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))
Alternative Name
POLG2 (POLG2 Products )
Synonyms
POLG2 antibody, im:7158733 antibody, si:ch211-157f15.3 antibody, HP55 antibody, MTPOLB antibody, PEOA4 antibody, POLB antibody, POLG-BETA antibody, POLGB antibody, mtpolb antibody, DNA polymerase gamma 2, accessory subunit antibody, polymerase (DNA directed), gamma 2, accessory subunit antibody, polymerase (DNA directed), gamma 2, accessory subunit L homeolog antibody, Polg2 antibody, POLG2 antibody, polg2 antibody, polg2.L antibody
Background
This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.,POLG2,HP55,MTPOLB,PEOA4,POLB,POLG-BETA,POLGB,Epigenetics & Nuclear Signaling,Endocrine & Metabolism,Mitochondrial metabolism,POLG2
Molecular Weight
54 kDa
Gene ID
11232
UniProt
Q9UHN1
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