POLE3 antibody (AA 1-147)
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- Target See all POLE3 Antibodies
- POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))
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Binding Specificity
- AA 1-147
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This POLE3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MAERPEDLNL PNAVITRIIK EALPDGVNIS KEARSAISRA ASVFVLYATS CANNFAMKGK RKTLNASDVL SAMEEMEFQR FVTPLKEALE AYRREQKGKK EASEQKKKDK DKKTDSEEQD KSRDEDNDED EERLEEEEQN EEEEVDN
- Cross-Reactivity
- Human, Mouse
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human POLE3 (NP_059139.3).
- Isotype
- IgG
- Top Product
- Discover our top product POLE3 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).
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RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).
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- Target
- POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))
- Alternative Name
- POLE3 (POLE3 Products)
- Background
- POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004],POLE3,CHARAC17,CHRAC17,YBL1,p17,Epigenetics & Nuclear Signaling,DNA Damage & Repair,POLE3
- Molecular Weight
- 16 kDa
- Gene ID
- 54107
- UniProt
- Q9NRF9
- Pathways
- DNA Damage Repair
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