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POLE3 antibody (AA 1-147)

POLE3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6145888
  • Target See all POLE3 Antibodies
    POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))
    Binding Specificity
    • 4
    • 3
    • 3
    • 2
    • 2
    AA 1-147
    Reactivity
    • 39
    • 20
    • 16
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 33
    • 6
    Rabbit
    Clonality
    • 36
    • 3
    Polyclonal
    Conjugate
    • 25
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This POLE3 antibody is un-conjugated
    Application
    • 22
    • 10
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MAERPEDLNL PNAVITRIIK EALPDGVNIS KEARSAISRA ASVFVLYATS CANNFAMKGK RKTLNASDVL SAMEEMEFQR FVTPLKEALE AYRREQKGKK EASEQKKKDK DKKTDSEEQD KSRDEDNDED EERLEEEEQN EEEEVDN
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human POLE3 (NP_059139.3).
    Isotype
    IgG
    Top Product
    Discover our top product POLE3 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Xiang, Laurent, Hsu, Nachtergaele, Lu, Sheng, Xu, Chen, Ouyang, Wang, Ling, Hsu, Zou, Jambhekar, He, Shi: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).

  • Target
    POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))
    Alternative Name
    POLE3 (POLE3 Products)
    Background
    POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004],POLE3,CHARAC17,CHRAC17,YBL1,p17,Epigenetics & Nuclear Signaling,DNA Damage & Repair,POLE3
    Molecular Weight
    16 kDa
    Gene ID
    54107
    UniProt
    Q9NRF9
    Pathways
    DNA Damage Repair
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