PLOD1 antibody (AA 488-727)

Catalog No. ABIN6145784

Product Details anti-PLOD1 Antibody

Target: PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))

Binding Specificity: AA 488-727

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLOD1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RQQDVFMFLT NRHTLGHLLS LDSYRTTHLH NDLWEVFSNP EDWKEKYIHQ NYTKALAGKL VETPCPDVYW FPIFTEVACD ELVEEMEHFG QWSLGNNKDN RIQGGYENVP TIDIHMNQIG FEREWHKFLL EYIAPMTEKL YPGYYTRAQF DLAFVVRYKP DEQPSLMPHH DASTFTINIA LNRVGVDYEG GGCRFLRYNC SIRAPRKGWT LMHPGRLTHY HEGLPTTRGT RYIAVSFVDP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 488-727 of human PLOD1 (NP_000293.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PLOD1

Target: PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))

Alternative Name: PLOD1 (PLOD1 Products)

Background: Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.,PLOD1,EDS6,LH,LH1,LLH,PLOD,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,PLOD1

Molecular Weight: 83 kDa/88 kDa

Gene ID: 5351

UniProt: Q02809