zgc:77476 antibody, wu:fc06g09 antibody, PNPLA9 antibody, MGC83523 antibody, PLA2G6 antibody, BB112799 antibody, iPLA(2)beta antibody, iPLA2 antibody, iPLA2beta antibody, CaI-PLA2 antibody, GVI antibody, INAD1 antibody, IPLA2-VIA antibody, NBIA2 antibody, NBIA2A antibody, NBIA2B antibody, PARK14 antibody, PLA2 antibody, iPla2 antibody, phospholipase A2, group VI (cytosolic, calcium-independent) antibody, phospholipase A2 group VI antibody, phospholipase A2 group VI S homeolog antibody, 85/88 kDa calcium-independent phospholipase A2 antibody, phospholipase A2, group VI antibody, pla2g6 antibody, PLA2G6 antibody, pla2g6.S antibody, LOC100445065 antibody, Pla2g6 antibody
Background
The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date.,PLA2G6,CaI-PLA2,GVI,INAD1,IPLA2-VIA,NBIA2,NBIA2A,NBIA2B,PARK14,PLA2,PNPLA9,iPLA2,iPLA2beta,Signal Transduction,PLA2G6