PLA2G1B antibody (AA 23-148)

Catalog No. ABIN6145724

Product Details anti-PLA2G1B Antibody

Target: PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))

Binding Specificity: AA 23-148

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: AVWQFRKMIK CVIPGSDPFL EYNNYGCYCG LGGSGTPVDE LDKCCQTHDN CYDQAKKLDS CKFLLDNPYT HTYSYSCSGS AITCSSKNKE CEAFICNCDR NAAICFSKAP YNKAHKNLDT KKYCQS

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-148 of human PLA2G1B (NP_000919.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PLA2G1B

Target: PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))

Alternative Name: PLA2G1B (PLA2G1B Products)

Synonyms: C133 antibody, CG4346 antibody, Dmel\\CG42237 antibody, Dmel_CG4346 antibody, PLA2 antibody, GB13351 antibody, bvPLA2 antibody, PLA2A antibody, PPLA2 antibody, sPLA(2)-IB antibody, Pla2a antibody, sPLA2IB antibody, PLA2G1B antibody, CG42237 gene product from transcript CG42237-RB antibody, phospholipase A2 antibody, phospholipase A2 group IB antibody, phospholipase A2, group IB, pancreas antibody, phospholipase A2 group IVA antibody, CG42237 antibody, PLA2 antibody, LOC100631065 antibody, Pla2 antibody, PLA2G1B antibody, Pla2g1b antibody, PLA2G4A antibody

Background: This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response.,PLA2G1B,PLA2,PLA2A,PPLA2,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Endocrine & Metabolism,Lipid Metabolism,PLA2G1B

Molecular Weight: 16 kDa

Gene ID: 5319

UniProt: P04054

Pathways: Inositol Metabolic Process, VEGF Signaling