PINK1 antibody (AA 282-581)

Catalog No. ABIN6145665

Product Details anti-PINK1 Antibody

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Binding Specificity: AA 282-581

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PINK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: TSSVPLLPGA LVDYPDVLPS RLHPEGLGHG RTLFLVMKNY PCTLRQYLCV NTPSPRLAAM MLLQLLEGVD HLVQQGIAHR DLKSDNILVE LDPDGCPWLV IADFGCCLAD ESIGLQLPFS SWYVDRGGNG CLMAPEVSTA RPGPRAVIDY SKADAWAVGA IAYEIFGLVN PFYGQGKAHL ESRSYQEAQL PALPESVPPD VRQLVRALLQ REASKRPSAR VAANVLHLSL WGEHILALKN LKLDKMVGWL LQQSAATLLA NRLTEKCCVE TKMKMLFLAN LECETLCQAA LLLCSWRAAL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 282-581 of human PINK1 (NP_115785.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-PINK1 antibody (ABIN6145665)

Ren, Li, Yan, Ma, Zhou, Xue, Zhang, Liu, Yang, Jia, Zhang, Zhang, Mu, Zhang, Da: "Adiponectin modulates oxidative stress-induced mitophagy and protects C2C12 myoblasts against apoptosis." in: Scientific reports, Vol. 7, Issue 1, pp. 3209, (2018) (PubMed).

Target Details for PINK1

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Alternative Name: PINK1 (PINK1 Products)

Synonyms: BEST:GH23468 antibody, CG4523 antibody, Dmel\\CG4523 antibody, PINK antibody, PINK1 antibody, dPINK1 antibody, dPink1 antibody, pink1 antibody, wu:fc39e12 antibody, zgc:101729 antibody, BRPK antibody, PARK6 antibody, 1190006F07Rik antibody, AU042772 antibody, AW557854 antibody, mFLJ00387 antibody, PTEN-induced putative kinase 1 antibody, PTEN induced putative kinase 1 antibody, Pink1 antibody, PINK1 antibody, pink1 antibody

Background: This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.,PINK1,BRPK,PARK6,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitophagy fission and fusion,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Neurodegenerative Diseases Markers,Cardiovascular,Heart,Cardiac metabolism,Mitochondrial Control of Autophagy,PINK1

Molecular Weight: 30 kDa/62 kDa

Gene ID: 65018

UniProt: Q9BXM7

Pathways: Autophagy