PHKG2 antibody (AA 237-406)

Catalog No. ABIN6145563

Product Details anti-PHKG2 Antibody

Target: PHKG2 (phosphorylase Kinase, gamma 2 (Testis) (PHKG2))

Binding Specificity: AA 237-406

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHKG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: RQILMLRMIM EGQYQFSSPE WDDRSSTVKD LISRLLQVDP EARLTAEQAL QHPFFERCEG SQPWNLTPRQ RFRVAVWTVL AAGRVALSTH RVRPLTKNAL LRDPYALRSV RHLIDNCAFR LYGHWVKKGE QQNRAALFQH RPPGPFPIMG PEEEGDSAAI TEDEAVLVLG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 237-406 of human PHKG2 (NP_000285.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PHKG2

Target: PHKG2 (phosphorylase Kinase, gamma 2 (Testis) (PHKG2))

Alternative Name: PHKG2 (PHKG2 Products)

Synonyms: PHKG2 antibody, MGC145608 antibody, zgc:55863 antibody, GSD9C antibody, 1500017I02Rik antibody, phosphorylase kinase catalytic subunit gamma 2 antibody, phosphorylase kinase, gamma 2 (testis) antibody, phosphorylase kinase, gamma 2 (testis) L homeolog antibody, PHKG2 antibody, phkg2 antibody, phkg2.L antibody, Phkg2 antibody

Background: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known as autosomal liver glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.,PHKG2,GSD9C,Cancer,Signal Transduction,Kinase,Endocrine & Metabolism,Carbohydrate metabolism,PHKG2

Molecular Weight: 43 kDa/46 kDa

Gene ID: 5261

UniProt: P15735

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process