PHC3 antibody (AA 100-300)

Catalog No. ABIN6145527

Product Details anti-PHC3 Antibody

Target: PHC3 (Polyhomeotic Homolog 3 (PHC3))

Binding Specificity: AA 100-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHC3 antibody is un-conjugated

Application: Immunofluorescence (IF)

Sequence: LSSSQLQSLA AVQASLSSGR PSTSPTGSVT QQSSMSQTSI NLSTSPTPAQ LISRSQASSS TSGSITQQTM LLGSTSPTLT ASQAQMYLRA QMLIFTPATT VAAVQSDIPV VSSSSSSSCQ SAATQVQNLT LRSQKLGVLS SSQNGPPKST SQTQSLTICH NKTTVTSSKI SQRDPSPESN KKGESPSLES RSTAVTRTSS I

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-300 of human PHC3 (NP_079223.3).

Isotype: IgG

Application Details

Application Notes: IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PHC3

Target: PHC3 (Polyhomeotic Homolog 3 (PHC3))

Alternative Name: PHC3 (PHC3 Products)

Synonyms: EDR3 antibody, HPH3 antibody, E030046K01Rik antibody, Edr3 antibody, Hph3 antibody, polyhomeotic homolog 3 antibody, polyhomeotic-like 3 (Drosophila) antibody, Phc3 antibody, PHC3 antibody

Background: Component of a Polycomb group (PcG multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.,PHC3,EDR3,HPH3,Epigenetics & Nuclear Signaling,Chromatin Remodeling,PHC3

Molecular Weight: 14 kDa/16 kDa/19 kDa/35 kDa/104 kDa/106 kDa/107 kDa

Gene ID: 80012

UniProt: Q8NDX5