PGA5 antibody (AA 63-180)

Catalog No. ABIN6145497

Product Details anti-PGA5 Antibody

Target: PGA5 (Pepsinogen 5, Group I (Pepsinogen A) (PGA5))

Binding Specificity: AA 63-180

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGA5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VDEQPLENYL DMEYFGTIGI GTPAQDFTVV FDTGSSNLWV PSVYCSSLAC TNHNRFNPED SSTYQSTSET VSITYGTGSM TGILGYDTVQ VGGISDTNQI FGLSETEPGS FLYYAPFD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 63-180 of human PGA5 (NP_055039.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PGA5

Target: PGA5 (Pepsinogen 5, Group I (Pepsinogen A) (PGA5))

Alternative Name: PGA5 (PGA5 Products)

Synonyms: PGA3 antibody, PGA4 antibody, 1110035E17Rik antibody, Pepf antibody, pepsinogen 5, group I (pepsinogen A) antibody, pepsinogen 5, group I antibody, PGA5 antibody, Pga5 antibody

Background: This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer.,PGA5,Pg5,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,Endocrine & Metabolism,PGA5

Molecular Weight: 41 kDa

Gene ID: 5222

UniProt: P0DJD9