PDK3 antibody (AA 137-406)
-
- Target See all PDK3 Antibodies
- PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
-
Binding Specificity
- AA 137-406
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PDK3 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- FGFDPFISTN IQYFLDRFYT NRISFRMLIN QHTLLFGGDT NPVHPKHIGS IDPTCNVADV VKDAYETAKM LCEQYYLVAP ELEVEEFNAK APDKPIQVVY VPSHLFHMLF ELFKNSMRAT VELYEDRKEG YPAVKTLVTL GKEDLSIKIS DLGGGVPLRK IDRLFNYMYS TAPRPSLEPT RAAPLAGFGY GLPISRLYAR YFQGDLKLYS MEGVGTDAVI YLKALSSESF ERLPVFNKSA WRHYKTTPEA DDWSNPSSEP RDASKYKAKQ
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 137-406 of human PDK3 (NP_005382.1).
- Isotype
- IgG
- Top Product
- Discover our top product PDK3 Primary Antibody
-
-
- Application Notes
- WB,1:500 - 1:2000
- Comment
-
HIGH QUALITY
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
- Alternative Name
- PDK3 (PDK3 Products)
- Synonyms
- pdk3 antibody, PDK3 antibody, 2610001M10Rik antibody, AI035637 antibody, zgc:158702 antibody, pyruvate dehydrogenase kinase 3 antibody, pyruvate dehydrogenase kinase, isozyme 3a antibody, pyruvate dehydrogenase kinase, isoenzyme 3 antibody, fragile site, 5-azacytidine type, common, fra(1)(q12) antibody, pyruvate dehydrogenase kinase, isozyme 3b antibody, PDK3 antibody, Pdk3 antibody, pdk3a antibody, pdk3 antibody, FRA1J antibody, pdk3b antibody
- Background
- The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PDK3,CMTX6,GS1-358P8.4,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Warburg Effect,PDK3
- Molecular Weight
- 46 kDa/48 kDa
- Gene ID
- 5165
- UniProt
- Q15120
- Pathways
- PI3K-Akt Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
-