PDE3B antibody (AA 400-660)
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- Target See all PDE3B Antibodies
- PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))
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Binding Specificity
- AA 400-660
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PDE3B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PLTPFPGFYP CSEIEDPAEK GDRKLNKGLN RNSLPTPQLR RSSGTSGLLP VEQSSRWDRN NGKRPHQEFG ISSQGCYLNG PFNSNLLTIP KQRSSSVSLT HHVGLRRAGV LSSLSPVNSS NHGPVSTGSL TNRSPIEFPD TADFLNKPSV ILQRSLGNAP NTPDFYQQLR NSDSNLCNSC GHQMLKYVST SESDGTDCCS GKSGEEENIF SKESFKLMET QQEEETEKKD SRKLFQEGDK WLTEEAQSEQ QTNIEQEVSL D
- Cross-Reactivity
- Human, Mouse
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 400-660 of human PDE3B (NP_000913.2).
- Isotype
- IgG
- Top Product
- Discover our top product PDE3B Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))
- Alternative Name
- PDE3B (PDE3B Products)
- Synonyms
- PDE3B antibody, HcGIP1 antibody, cGIPDE1 antibody, 9830102A01Rik antibody, AI847709 antibody, phosphodiesterase 3B antibody, phosphodiesterase 3B, cGMP-inhibited antibody, si:ch211-79e4.4 antibody, phosphodiesterase 3B L homeolog antibody, PDE3B antibody, pde3b antibody, Pde3b antibody, si:ch211-79e4.4 antibody, pde3b.L antibody
- Background
- Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.,PDE3B,HcGIP1,cGIPDE1,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Insulin Receptor Signaling Pathway,PDE3B
- Molecular Weight
- 118 kDa/124 kDa
- Gene ID
- 5140
- UniProt
- Q13370
- Pathways
- Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process
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