PCCA antibody (AA 449-728)

Catalog No. ABIN6145279

Product Details anti-PCCA Antibody

Target: PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

Binding Specificity: AA 449-728

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCCA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ISKLITYGSD RTEALKRMAD ALDNYVIRGV THNIALLREV IINSRFVKGD ISTKFLSDVY PDGFKGHMLT KSEKNQLLAI ASSLFVAFQL RAQHFQENSR MPVIKPDIAN WELSVKLHDK VHTVVASNNG SVFSVEVDGS KLNVTSTWNL ASPLLSVSVD GTQRTVQCLS REAGGNMSIQ FLGTVYKVNI LTRLAAELNK FMLEKVTEDT SSVLRSPMPG VVVAVSVKPG DAVAEGQEIC VIEAMKMQNS MTAGKTGTVK SVHCQAGDTV GEGDLLVELE

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 449-728 of human PCCA (NP_000273.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:3000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PCCA

Target: PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

Alternative Name: PCCA (PCCA Products)

Background: The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.,PCCA,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,PCCA

Molecular Weight: 75 kDa/77 kDa/80 kDa

Gene ID: 5095

UniProt: P05165

Pathways: Monocarboxylic Acid Catabolic Process