PBXIP1 antibody (AA 1-190)

Catalog No. ABIN6145273

Product Details anti-PBXIP1 Antibody

Target: PBXIP1 (Pre-B-Cell Leukemia Homeobox Interacting Protein 1 (PBXIP1))

Binding Specificity: AA 1-190

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PBXIP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MASCPDSDNS WVLAGSESLP VETLGPASRM DPESERALQA PHSPSKTDGK ELAGTMDGEG TLFQTESPQS GSILTEETEV KGTLEGDVCG VEPPGPGDTV VQGDLQETTV VTGLGPDTQD LEGQSPPQSL PSTPKAAWIR EEGRCSSSDD DTDVDMEGLR RRRGREAGPP QPMVPLAVEN QAGGEGAGGE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PBXIP1 (NP_065385.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PBXIP1

Target: PBXIP1 (Pre-B-Cell Leukemia Homeobox Interacting Protein 1 (PBXIP1))

Alternative Name: PBXIP1 (PBXIP1 Products)

Synonyms: im:7138234 antibody, wu:fb12b01 antibody, zgc:158151 antibody, 4732463H20Rik antibody, HPIP antibody, pre-B-cell leukemia homeobox interacting protein 1b antibody, PBX homeobox interacting protein 1 antibody, pre B cell leukemia transcription factor interacting protein 1 antibody, pbxip1b antibody, PBXIP1 antibody, Pbxip1 antibody

Background: The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.,PBXIP1,HPIP,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Signal Transduction,PBXIP1

Molecular Weight: 72 kDa/77 kDa/80 kDa

Gene ID: 57326

UniProt: Q96AQ6