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PBX1 antibody (AA 311-430)

PBX1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6145269
  • Target See all PBX1 Antibodies
    PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
    Binding Specificity
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 311-430
    Reactivity
    • 24
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 15
    • 8
    • 1
    Rabbit
    Clonality
    • 17
    • 7
    Polyclonal
    Conjugate
    • 20
    • 2
    • 1
    • 1
    This PBX1 antibody is un-conjugated
    Application
    • 18
    • 14
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    VTATNVSAHG SQANSPSTPN SAGSSSSFNM SNSGDLFMSV QSLNGDSYQG AQVGANVQSQ VDTLRHVISQ TGGYSDGLAA SQMYSPQGIS ANGGWQDATT PSSVTSPTEG PGSVHSDTSN
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 311-430 of human PBX1 (NP_002576.1).
    Isotype
    IgG
    Top Product
    Discover our top product PBX1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
    Alternative Name
    PBX1 (PBX1 Products)
    Background
    This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis and required for skeletal patterning and programming. A chromosomal translocation, t(1,19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PBX1,Epigenetics & Nuclear Signaling,Transcription Factors,Stem Cells,Hematopoietic Progenitors,PBX1
    Molecular Weight
    38 kDa/46 kDa
    Gene ID
    5087
    UniProt
    P40424
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