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PACS1 antibody (AA 420-560)
PACS1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PACS1 Antibody
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Target
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PACS1
(phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))
Binding Specificity
All epitopes for PACS1 antibodies
AA 420-560
Reactivity
All reactivities for PACS1 antibodies
Human
Host
All hosts for PACS1 antibodies
Rabbit
Clonality
All clonalities for PACS1 antibodies
Polyclonal
Conjugate
All conjugates for PACS1 antibodies
This PACS1 antibody is un-conjugated
Application
All applications for PACS1 antibodies
Western Blotting (WB)
Sequence
SKGSLGKDTT SPMELAALEK IKSTWIKNQD DSLTETDTLE ITDQDMFGDA STSLVVPEKV KTPMKSSKTD LQGSASPSKV EGVHTPRQKR STPLKERQLS KPLSERTNSS DSERSPDLGH STQIPRKVVY DQLNQILVSD A
Cross-Reactivity
Human
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 420-560 of human PACS1 (NP_060496.2).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB,1:1000 - 1:3000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for PACS1
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Target
PACS1
(phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))
Alternative Name
PACS1 (PACS1 Products )
Synonyms
MRD17 antibody, AI325977 antibody, Pacs-1 antibody, phosphofurin acidic cluster sorting protein 1 antibody, PACS1 antibody, Pacs1 antibody
Background
This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.,PACS1,MRD17,SHMS,Signal Transduction,Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,PACS1
Molecular Weight
104 kDa/109 kDa
Gene ID
55690
UniProt
Q6VY07
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