Oncostatin M Receptor antibody (AA 30-330)

Catalog No. ABIN6145074

Product Details anti-Oncostatin M Receptor Antibody

Target: Oncostatin M Receptor (OSMR)

Binding Specificity: AA 30-330

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Oncostatin M Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LPLTPVSLKV STNSTRQSLH LQWTVHNLPY HQELKMVFQI QISRIETSNV IWVGNYSTTV KWNQVLHWSW ESELPLECAT HFVRIKSLVD DAKFPEPNFW SNWSSWEEVS VQDSTGQDIL FVFPKDKLVE EGTNVTICYV SRNIQNNVSC YLEGKQIHGE QLDPHVTAFN LNSVPFIRNK GTNIYCEASQ GNVSEGMKGI VLFVSKVLEE PKDFSCETED FKTLHCTWDP GTDTALGWSK QPSQSYTLFE SFSGEKKLCT HKNWCNWQIT QDSQETYNFT LIAENYLRKR SVNILFNLTH R

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-330 of human OSMR (NP_003990.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Oncostatin M Receptor

Target: Oncostatin M Receptor (OSMR)

Alternative Name: OSMR (OSMR Products)

Synonyms: OSMRB antibody, PLCA1 antibody, oncostatin M receptor antibody, OSMR antibody, Osmr antibody

Background: This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,OSMR,IL-31R-beta,IL-31RB,OSMRB,PLCA1,OSMR

Molecular Weight: 39 kDa/110 kDa

Gene ID: 9180

UniProt: Q99650

Pathways: JAK-STAT Signaling, Growth Factor Binding