NUMB antibody (AA 521-640)
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- Target See all NUMB Antibodies
- NUMB (Numb Homolog (NUMB))
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Binding Specificity
- AA 521-640
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NUMB antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- SQMVANVFGT AGHPQAAHPH QSPSLVRQQT FPHYEASSAT TSPFFKPPAQ HLNGSAAFNG VDDGRLASAD RHTEVPTGTC PVDPFEAQWA ALENKSKQRT NPSPTNPFSS DLQKTFEIEL
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 521-640 of human NUMB (NP_003735.3).
- Isotype
- IgG
- Top Product
- Discover our top product NUMB Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- NUMB (Numb Homolog (NUMB))
- Alternative Name
- NUMB (NUMB Products)
- Synonyms
- C14orf41 antibody, S171 antibody, c14_5527 antibody, Nb antibody, NUMB, endocytic adaptor protein antibody, numb homolog (Drosophila) antibody, NUMB antibody, Numb antibody, numb antibody
- Background
- The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.,NUMB,C14orf41,S171,c14_5527,Signal Transduction,Cell Biology & Developmental Biology,Notch Signaling Pathway,Neuroscience,Stem Cells,NUMB
- Molecular Weight
- 37 kDa/48-70 kDa
- Gene ID
- 8650
- UniProt
- P49757
- Pathways
- Cell-Cell Junction Organization
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