NSUN6 antibody (AA 220-469)

Catalog No. ABIN6144879

Product Details anti-NSUN6 Antibody

Target: NSUN6 (NOP2/Sun Domain Family, Member 6 (NSUN6))

Binding Specificity: AA 220-469

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSUN6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: NLPSALVSHV LNPQPGEKIL DLCAAPGGKT THIAALMHDQ GEVIALDKIF NKVEKIKQNA LLLGLNSIRA FCFDGTKAVK LDMVEDTEGE PPFLPESFDR ILLDAPCSGM GQRPNMACTW SVKEVASYQP LQRKLFTAAV QLLKPEGVLV YSTCTITLAE NEEQVAWALT KFPCLQLQPQ EPQIGGEGMR GAGLSCEQLK QLQRFDPSAV PLPDTDMDSL REARREDMLR LANKDSIGFF IAKFVKCKST

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 220-469 of human NSUN6 (NP_872349.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NSUN6

Target: NSUN6 (NOP2/Sun Domain Family, Member 6 (NSUN6))

Alternative Name: NSUN6 (NSUN6 Products)

Synonyms: 4933403D21Rik antibody, 4933414E04Rik antibody, NOPD1 antibody, Nopd1 antibody, putative methyltransferase NSUN6 antibody, NOL1/NOP2/Sun domain family member 6 antibody, NOP2/Sun RNA methyltransferase family member 6 antibody, NOP2/Sun domain family, member 6 antibody, Tsp_01405 antibody, Nsun6 antibody, NSUN6 antibody

Background: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in tRNA(Thr(TGT and tRNA(Cys(GCA. In vitro also methylates tRNA(Thr(AGT. Methylation requires, in the acceptor stem region, the presence of the 3'-CCA terminus, the target site C72, the discriminator base U73, and the second and third base pairs (2:71 and 3:70 in the tRNA substrates.,NSUN6,4933414E04Rik,ARL5B-AS1,NOPD1,Epigenetics & Nuclear Signaling,NSUN6

Molecular Weight: 51 kDa

Gene ID: 221078

UniProt: Q8TEA1