Neurogranin antibody (AA 1-78)

Catalog No. ABIN6144855

Product Details anti-Neurogranin Antibody

Target: Neurogranin (NRGN)

Binding Specificity: AA 1-78

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurogranin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MDCCTENACS KPDDDILDIP LDDPGANAAA AKIQASFRGH MARKKIKSGE RGRKGPGPGG PGGAGVARGG AGGGPSGD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-78 of human NRGN (NP_001119653.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Neurogranin

Target: Neurogranin (NRGN)

Alternative Name: NRGN (NRGN Products)

Synonyms: RC3 antibody, hng antibody, 0710001B06Rik antibody, AI838505 antibody, NG antibody, NG/RC3 antibody, Pss1 antibody, R75334 antibody, zgc:158686 antibody, neurogranin antibody, neurogranin (protein kinase C substrate, RC3) b antibody, NRGN antibody, Nrgn antibody, nrgnb antibody

Background: Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.,NRGN,RC3,hng,Signal Transduction,Kinase,Endocrine & Metabolism,Neuroscience,Calcium Signaling,NRGN

Molecular Weight: 7 kDa

Gene ID: 4900

UniProt: Q92686