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NPHP3 antibody (AA 1-130)
NPHP3
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NPHP3 Antibody
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Target
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NPHP3
(Nephronophthisis 3 (Adolescent) (NPHP3))
Binding Specificity
All epitopes for NPHP3 antibodies
AA 1-130
Reactivity
All reactivities for NPHP3 antibodies
Human
Host
All hosts for NPHP3 antibodies
Rabbit
Clonality
All clonalities for NPHP3 antibodies
Polyclonal
Conjugate
All conjugates for NPHP3 antibodies
This NPHP3 antibody is un-conjugated
Application
All applications for NPHP3 antibodies
Western Blotting (WB)
Sequence
MGTASSLVSP AGGEVIEDTY GAGGGEACEI PVEVKPKARL LRNSFRRGAG AAAGAGPGSL PRGVGAGGLL GASFKSTGSS VPELEYAAAE YERLRKEYEI FRVSKNQELL SMGRREAKLD TENKRLRAEL
Cross-Reactivity
Human, Mouse
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human NPHP3 (NP_694972.3).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB,1:200 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for NPHP3
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Target
NPHP3
(Nephronophthisis 3 (Adolescent) (NPHP3))
Alternative Name
NPHP3 (NPHP3 Products )
Synonyms
si:dkey-56l10.1 antibody, MKS7 antibody, NPH3 antibody, RHPD antibody, 3632410F03Rik antibody, AI550417 antibody, C230078J01 antibody, D330020E01Rik antibody, pcy antibody, RGD1563856 antibody, nephronophthisis 3 antibody, nephrocystin 3 antibody, nephronophthisis 3 (adolescent) antibody, nphp3 antibody, NPHP3 antibody, Nphp3 antibody
Background
This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin, it is required for normal ciliary development, and it functions in renal tubular development. Mutations in this gene are associated with nephronophthisis type 3, and also with renal-hepatic-pancreatic dysplasia, and Meckel syndrome type 7. Naturally occurring read-through transcripts exist between this gene and the downstream ACAD11 (acyl-CoA dehydrogenase family, member 11) gene.,NPHP3,CFAP31,MKS7,NPH3,RHPD,RHPD1,SLSN3,NPHP3
Molecular Weight
15 kDa/19 kDa/26 kDa/71 kDa/73 kDa/79 kDa/150 kDa
Gene ID
27031
UniProt
Q7Z494
Pathways
cAMP Metabolic Process
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